Convertech International 2023 4th
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is to create green chemicals that are not derived from pet-rochemicals. According to Tomohito Ihara, CEO of GEI, the company's core technology is a bioprocessing technology developed at the Research Institute of Innovative Technol-ogy for the Earth (RITE). Compared with traditional fermen-tation techniques, this technology is characterized by the utilization of non-edible biomass, high productivity, and the production of low-cost green chemicals.and gradually scales up from a few liters to tens of liters, hundreds of liters, thousands of liters, and even tens of thousands of liters. However, by rapidly scaling from tens of liters to, say, hundreds of kiloliters, we can reduce costs and accelerate development. Here, we offer such technol-ogies, and we can also assess the commercial viability by determining the market prices of the products, appropriate production volumes, cost calculations, and conducting life cycle assessment (LCA) analyses.NEDO has announced that by fiscal 2026 it will be work-ing on production verification of over 16 bio-derived com-pounds for practical use.300L BioreactorPrototype Room Overview3000L Bioreactor47Scale-up also accelerates development of chemicals and fuelsBiofoundry Institute Director, Mr. Atsushi Kojo led the tour of the facility. According to Kojo, a key feature of the institute is its ability to support full-scale commercialization, rather than just providing contract cultivation. "Products derived from microorganisms vary depending on the user, includ-ing not only chemicals but also some fuel-like substances. Such microbial cultivation typically starts with small flasks 300L and 3000L culture tanks for scale-up[Prototype Room]The prototype room is the main building of the institute. In-side are installed bioreactors for scale-up, with capacities of 300 liters and 3000 liters, respectively. These bioreactors are typically equipped with 2 to 3 times the number of sen-sors (over 6 sensors) compared to regular setups. These sensors measure parameters such as temperature, pH, nitrogen and oxygen concentrations in real time, allowing simulation of conditions similar to those found in commer-cial-scale bioreactors.Equipped with centrifugal separator and inactivation tankMicrobial nutrients are typically sugars such as glucose. These are gradually added to the bioreactors through a fed-

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